Innovative Research Award
Fang Lyu
Jiangsu Academy of Agricultural Sciences, China
Fang Lyu is a researcher affiliated with the Jiangsu Academy of Agricultural Sciences whose published work focuses on veterinary science, with particular attention to vaccine formulation, lyophilization, thermal stability, process optimization, and scale-up. The available publication record includes studies addressing live Newcastle disease vaccines, pseudorabies virus, combined Newcastle-disease–infectious-bronchitis vaccines, and strategies for improving the quality and stability of lyophilized animal vaccines. [1][4][5]
Abstract
Fang Lyu’s research record in veterinary science is centered on the development and optimization of stabilization and drying technologies for animal vaccines. His publications examine vacuum-foam drying and lyophilization as approaches for improving the thermal stability, storage performance, and practical processing of live vaccines. Research involving Newcastle disease vaccine has addressed process optimization, thermostability, shelf-life, and pilot-scale evaluation, while related work has examined lyophilization-induced effects in pseudorabies virus and the design and scale-up of thermostable combined vaccines. [2][3][4][5] A 2026 review further places these approaches within broader strategies for improving the quality of lyophilized animal vaccines. [1]
Keywords
Keywords: Fang Lyu; Veterinary Science; animal vaccines; lyophilization; freeze-drying; vacuum-foam drying; Newcastle disease vaccine; pseudorabies virus; vaccine thermostability; process optimization; vaccine shelf-life; pilot-scale evaluation.
Introduction
The stability of biological products during storage, transport, and use is an important consideration in veterinary vaccine development. Live vaccines can be particularly sensitive to environmental conditions, making formulation and drying processes relevant to product quality and practical deployment. Lyophilization, commonly known as freeze-drying, is one established strategy for stabilizing biological materials, while alternative drying approaches such as vacuum-foam drying have also been investigated for live veterinary vaccines. [1][5][2][4]
Research Profile
The available bibliographic information identifies Fang Lyu with the subject area of Veterinary Science and an affiliation with the Jiangsu Academy of Agricultural Sciences. The supplied Scopus profile records 8 documents, 171 citations, and an h-index of 7. These bibliometric values provide a quantitative description of the indexed research record but do not, by themselves, measure the quality or practical significance of individual studies.[2][3][4]
Research Contributions
Lyu’s research contributions can be organized around several interconnected areas of veterinary vaccine technology:
- Lyophilization and vaccine stabilization: Research examines the effects and optimization of freeze-drying processes for animal vaccines, including broader strategies for improving lyophilized vaccine quality. [1][2]
- Newcastle disease vaccine development: Studies have investigated thermostable vacuum-foam-dried Newcastle disease vaccines, including process optimization and pilot-scale evaluation. [4]
- Thermal stability and shelf-life: Research has evaluated vacuum-foam drying as a method for enhancing thermal stability and supporting long-term shelf-life of live-attenuated Newcastle disease virus vaccine. [5]
Publications
The supplied publication record includes peer-reviewed articles and an online-first study covering vaccine lyophilization, vacuum-foam drying, thermostability, process development, and scale-up.
- Huang F, Jiao J, Wang Z, Jie H, He J, Zuo X, Zhao Y, Lu Y, Gu J, Lyu F. Improving the Quality of Lyophilized Animal Vaccines: A Review of Optimization Strategies for Freeze-Drying Processes. Veterinary Sciences. 2026;13:972.
- Jiao J, Zhao Y, He J, Zeng M, Zuo X, Jie H, Zhao Y, Zhou B, Lyu F, Lu Y. Preliminary analysis of lyophilization-induced effects on pseudorabies virus strain Bartha-K61.
- Sun W, Zuo X, Jie H, Zhu Y, Xie L, Wang J, He J, Zhou B, Li X, Lyu F, Lu Y. Thermostable lyophilization procedure design and process scale-up for combined Newcastle-disease-infectious-bronchitis live vaccine.
Research Impact
The supplied Scopus metrics indicate 171 citations across 8 indexed documents and an h-index of 7. These figures describe the documented citation footprint of the research profile. The publication topics also demonstrate continuity between methodological research and application-oriented vaccine development, particularly through studies addressing thermostability, shelf-life, process optimization, and scale-up. [4][5]
Award Suitability
The documented research themes provide a substantive basis for considering Fang Lyu in connection with an Innovative Research Award within the International Popular Scientist Awards framework. The record contains research on vaccine stabilization technologies, lyophilization optimization, vacuum-foam drying, thermal stability, shelf-life, and pilot-scale process evaluation. [1][4][5]
Conclusion
Fang Lyu’s research profile is characterized by a focused contribution to veterinary vaccine technology, particularly the stabilization and processing of live animal vaccines. The available publications document work spanning lyophilization, vacuum-foam drying, thermostability, shelf-life, process optimization, and scale-up. [1][3][4][5] Together with the supplied bibliometric record, these publications provide a structured basis for documenting the researcher’s academic contribution in veterinary science.
External Links
References
- Huang F, Jiao J, Wang Z, Jie H, He J, Zuo X, Zhao Y, Lu Y, Gu J, Lyu F. Improving the Quality of Lyophilized Animal Vaccines: A Review of Optimization Strategies for Freeze-Drying Processes. Veterinary Sciences. 2026;13:972.
https://doi.org/10.3390/vetsci13090972
- Jiao J, Zhao Y, He J, Zeng M, Zuo X, Jie H, Zhao Y, Zhou B, Lyu F, Lu Y. Preliminary analysis of lyophilization-induced effects on pseudorabies virus strain Bartha-K61. Acta Veterinaria et Zootechnica Sinica.
- Sun W, Zuo X, Jie H, Zhu Y, Xie L, Wang J, He J, Zhou B, Li X, Lyu F, Lu Y. Thermostable lyophilization procedure design and process scale-up for combined Newcastle-disease-infectious-bronchitis live vaccine. China Animal Husbandry & Veterinary Medicine.
- Lyu F, Zhao Y, Zuo X, Nyide B, Deng B, Zhou M, Hou J, Jiao J, Zeng M, Jie H, Olaniran A, Lu Y, Khoza T. Thermostable vacuum-foam-dried Newcastle-disease vaccine: Process optimization and pilot-scale evaluation. Applied Microbiology and Biotechnology.
https://doi.org/10.1007/s00253-024-13174-7
- Lyu F, Zhao Y, Lu Y, Zuo X, Deng B, Zeng M, Wang J, Olaniran A, Hou J, Khoza T. Vacuum-foam-drying enhances thermal stability and long-term shelf-life of live-attenuated Newcastle-disease virus vaccine.
https://doi.org/10.1208/s12249-022-02440-4
- Elsevier. (n.d.). Scopus author details: Fang Lyu, Author ID 57191486161. Scopus.
https://www.scopus.com/authid/detail.uri?authorId=57191486161