Prof. Nisrin El Mlili is a distinguished neuroscientist and academic leader with extensive expertise in cellular and molecular mechanisms underlying neurological disorders, particularly those associated with hepatic encephalopathy and glutamatergic signaling. Her research primarily investigates the modulation of motor activity through neuronal circuits and metabotropic glutamate receptors, with a focus on hyperammonemia induced alterations in brain function. She has contributed significantly to understanding how chronic liver dysfunction affects neural pathways, integrating advanced neurochemical, electrophysiological, and behavioral approaches. Prof. El Mlili has published in high-impact, peer-reviewed journals, reflecting her commitment to advancing neuroscience knowledge through rigorous experimentation and translational relevance. Beyond her research, she is recognized for her leadership in higher education and academic governance, mentoring emerging scholars and promoting scientific collaboration. Her work bridges fundamental neuroscience with applied clinical contexts, offering insights into the pathophysiology of brain disorders and potential therapeutic targets. Her scholarship demonstrates a consistent focus on unraveling complex neurobiological processes and contributing to the broader scientific community through high quality publications and collaborative research initiatives, establishing her as an influential figure in both neuroscience research and academic development.
Profiles: Orcid | Google Scholar
Featured Publications
Cauli, O., Rodrigo, R., Llansola, M., Montoliu, C., Monfort, P., Piedrafita, B., … & Felipo, V. (2009). Glutamatergic and GABAergic neurotransmission and neuronal circuits in hepatic encephalopathy. Metabolic Brain Disease, 24(1), 69–80.
Felipo, V., Ordoño, J. F., Urios, A., El Mlili, N., Giménez‐Garzó, C., Aguado, C., … & Montoliu, C. (2012). Patients with minimal hepatic encephalopathy show impaired mismatch negativity correlating with reduced performance in attention tests. Hepatology, 55(2), 530–539.
Montoliu, C., Cauli, O., Urios, A., El Mlili, N., Serra, M. A., Giner-Duran, R., … & Felipo, V. (2011). 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis. The American Journal of Gastroenterology, 106(9), 1620–1627.
Llansola, M., Rodrigo, R., Monfort, P., Montoliu, C., Kosenko, E., Cauli, O., … & Felipo, V. (2007). NMDA receptors in hyperammonemia and hepatic encephalopathy. Metabolic Brain Disease, 22(3), 321–335.
Dadsetan, S., Balzano, T., Forteza, J., Agusti, A., Cabrera-Pastor, A., … & Felipo, V. (2016). Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. Journal of Neuroinflammation, 13(1), 245.